Peter Juergen Cnota;Beatrix Fyrnys;Istvan Szelenyi;Joachim Maus
发明人:
Joachim Maus,Peter Juergen Cnota,Istvan Szelenyi,Beatrix Fyrnys
申请号:
US12365003
公开号:
US08097605B2
申请日:
2009.02.03
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a combination of an inhaled/oral PDE 4 inhibitor in combination with inhaled anticholinergic bronchodilators (muscarinic receptor antagonists), preferentially Roflumilast or AWD-12-281 and R,R-glycopyrrolate, for symptomatic or prophylactic treatment of respiratory diseases, especially those accompanied by obstruction or inflammation such as chronic obstructive pulmonary disease (COPD) or asthma. It further comprises the presentation of this combination in a locally applied (inhaled) formulation and application in an inhalation device for instance in the Novolizer®.