The invention proposes a novel method of treatment of patients with chronic kidney disease (CKD). The method includes two stage transplantations of a patients kidney: first, one of kidneys of the patient with CKD is transplanted into a young healthy animal recipient (preferably a pig), whereas a kidney of a living person or cadaver or an animal recipient is temporarily transplanted into the body of the patient. Homeostatic factors of the animal recipient will cause the transplanted kidney recovery. In the second stage, the recovered kidney is autotransplantated back to the patient. Up to this time both the animal recipient and the patient are treated by immunosuppressive drugs.If an allogenic kidney is transplanted into the patients body, the patients kidney is transplanted into the body of a young healthy pig and after its recovery the patients kidney re-transplanted instead of the allogenic kidney.
