A kind of combination sensor is provided, at least one medical treatment of measurement or clinical sign are suitable for. Combination sensor includes: fabric sensor, is configured to determine that the pressure for being applied to the combination sensor And optical sensor. Optical sensor generally includes at least one fibre optical sensor (FOS), and may be used as photoplethysmographic (PPG) sensor, optionally, reflective-mode photoplethysmographic (PPG) sensor. Combination sensor can eliminate the motion artifacts as caused by the movement of the subject of wearable sensors, to be conducive to the long-term dynamics monitoring to subject.