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Compositions solides pharmaceutiques contenant des sels ibuprofènes
专利权人:
Zambon S.p.A.
发明人:
申请号:
EP11009132.9
公开号:
EP2594266A1
申请日:
2011.11.17
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
A pharmaceutical, non-effervescent, solid composition comprising a mixture of a pharmaceutically effective amount of a ibuprofen salt and a pharmaceutically acceptable strong base in a molar ratio of from 1:0.01 to 1:0.8, said composition being such that, when dissolved in a suitable liquid for dilution, imparts a pH value ranging from 9 to 9.5 to the obtained solution, which do not cause sensory irritation to the oral cavity especially to the back of the mouth and throat, when swallowed.
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