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Excipients granulated product and a method for producing the same, as well as tablets
专利权人:
フロイント産業株式会社
发明人:
古川 研二
申请号:
JP2013033265
公开号:
JP6088848B2
申请日:
2013.02.22
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide an excipient agglomerated material, production method thereof, and a tablet using the excipient agglomerated material which can inhibit aggregation in spite of long time storage, has high moldability, can be obtained excellent tablet hardness, and further has a low reactivity with the component contained in the tablet.SOLUTION: The invention relates to an excipient agglomerated material and the like which can be obtained by flowing powders containing a disaccharide sugar alcohol in a fluidized bed granulator, and by spraying a disaccharide sugar alcohol to the powders to granulate, and the volume mean particle diameter of the agglomerated material obtained by the granulation is 70 μm-170 μm, and the aggregation rate is 30% or less when the agglomerated material is stored for two weeks under the environment of 40°C, 75% of relative humidity.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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