PROBLEM TO BE SOLVED: To provide a method for producing fine particles, the method being capable of efficiently obtaining fine particles having a narrow particle size distribution and being excellent in continuous productivity.SOLUTION: A method for producing fine particles comprises: a discharge step in which vibrations are applied to a liquid containing a physiologically active substance contained in a liquid column resonance liquid chamber to form a standing wave due to a liquid column resonance, and the liquid is discharged from a discharge port formed in the amplitude direction of the standing wave in a region serving as an antinode of the standing wave； and a fine particle forming step in which the liquid is dried to form fine particles. Preferably, the physiologically active substance is a pharmaceutical compound, etc.SELECTED DRAWING: None【課題】粒度分布が狭い微粒子を効率よく得ることができ、連続生産性に優れる微粒子の製造方法の提供。【解決手段】液柱共鳴液室内に収容された、生理活性物質を含む液体に振動を付与して液柱共鳴による定在波を形成し、前記定在波の腹となる領域に、前記定在波の振幅方向に形成された吐出口から前記液体を吐出する吐出工程と、吐出した前記液体を乾燥して微粒子を形成する微粒子形成工程と、を含む微粒子の製造方法である。前記生理活性物質が、医薬化合物である態様などが好ましい。【選択図】なし
