The present invention relates to a composite of a hydrophilicity photosensitizer and a biocompatible polymer for being effectively used in photodynamics diagnosis or treatment, and a method for manufacturing the same, and more particularly, to a composite for photodynamics diagnosis or treatment and a method for manufacturing the same, wherein the biocompatible polymer and the hydrophilicity photosensitizer are combined by an ionic bond and the biocompatible polymer surrounds the circumference of the hydrophilicity photosensitizer. The composites according to the present invention uses the biocompatible polymer, which has an electric charge by being ionized in a water system, so as to be combined with an electric charge (an electric charge opposite to an electric charge of the polymer) of the hydrophil photosensitizer, and thereby providing excellent accumulation properties of the hydrophil photosensitizers in which internalizing into cancer cells is difficult to due to the electric charge on the surfaces thereof such that not only the effect of apoptosis of cancer cells during near infrared radiation increases but also the composite is stably maintained during a blood circulation process. Thus, the composites of the present invention does not exhibit cytotoxicity to normal cells and produces excellent effects in in-vivo stability, and therefore, can be effectively used in diagnosis or treatment of diseases using photodynamics.COPYRIGHT KIPO 2014본 발명은 액상 형태인 콜린알포세레이트를 함유하는 약학적 조성물 및 이의 제조방법에 관한 것으로 고체 형태의 제형화가 가능한 콜린알포세레이트를 함유하고 특히 콜린알포세레이트의 부착 응집성을 개선할 수 있는 약학 제제, 및 그의 제조방법에 관한 것이다. 보다 구체적으로는, 호스트 및 게스트로 이루어지고, 상기 게스트가 콜린알포세레이트인 포접 화합물을 포함하는 약학 제제이다. 본 발명의 콜린알포세레이트를 함유하는 약학 제제는, 보관 안정성, 복용 편의성이 뛰어나고, 유해성 논란이 없으며, 제조방법 간단하고 별도의 제조장치가 필요없어 생산비용이 적게 소요되는 효과가 있다.
