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SELECTING AND STABILIZING dsRNA CONSTRUCTS
专利权人:
Scott C. Johnson;James K. Roberts;GREGORY R. HECK;Jean C. Goley;Tichafa R. I. Munyikwa;Ty T. Vaughn
发明人:
GREGORY R. HECK,Tichafa R. I. Munyikwa,Jean C. Goley,James K. Roberts,Scott C. Johnson,Ty T. Vaughn
申请号:
US13305688
公开号:
US20120192317A1
申请日:
2011.11.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The invention provides methods for selecting nucleotide sequences that yield dsRNA-mediated gene suppression in a target organism and enable their uptake by the target organism. The invention further provides expression constructs that confer stabilized expression of such sequences in a transgenic host cell, and methods for their use. Also provided are organisms, cells and tissues prepared by a method of the invention.
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