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TREATMENT OF POST-TRAUMATIC STRESS DISORDER USING ALLOCATED MYCOBACTERIUM
专利权人:
ИММОДЬЮЛОН ТЕРАПЬЮТИКС ЛИМИТЕД (GB)
发明人:
ЭКЛ Чарльз (GB),ГРЭНДЖ Джон (GB)
申请号:
RU2015114256
公开号:
RU2015114256A
申请日:
2013.09.17
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. The use of isolated Mycobacterium to prevent post-traumatic stress disorder (PTSD) and the symptoms associated with such a disorder. The use of claim 1, wherein Mycobacterium contains whole cell Mycobacterium. 3. The use of claim 1, wherein Mycobacterium contains a non-pathogenic heat-killed Mycobacterium. 4. The use of claim 3, wherein the non-pathogenic heat-killed Mycobacterium is selected from M.vaccae, M.obuense, M.parafortuitum, M.aurum, M.indicus pranii, and combinations thereof. The use of claim 4, wherein Mycobacterium is M.vaccae or M.obuense. 6. The use of claim 1, wherein Mycobacterium is a roughened version. The use of Mycobacterium according to claim 1 in the form of a vaccine composition, optionally containing an adjuvant. The use according to claim 1, where Mycobacterium is intended for administration to the military. The use of claim 1, wherein Mycobacterium is intended to be administered in repeated doses. The use according to claim 1, wherein Mycobacterium is present in a unit dose containing an effective amount of non-pathogenic heat-killed Mycobacterium from 10 to 10 cells. The use according to claim 1, wherein Mycobacterium is intended to be administered by parenteral, oral, sublingual, nasal, or pulmonary routes. The use of claim 11, wherein Mycobacterium is intended for administration by the oral route. The use of claim 11, wherein the parenteral method is selected from subcutaneous, intradermal, subdermal, intraperitoneal, intravenous or intravesical injection. The use according to claim 1, where Mycobacterium prevents at least one sign or symptom of post-traumatic stress disorder, where the sign or symptom is selected from disorganized or agitated behavior, problems with pain perception and pain resistance, headache, difficulty falling asleep or maintaining sleep, recurring game reflecting aspects of trauma, frightening dreams with lack1. Применение выделенной Mycobacterium для предупреждения посттравматического стрессового расстройства
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