Reagents and methods for identifying, enriching, and/or expanding antigen-specific T cells

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专利权人:

THE JOHNS HOPKINS UNIVERSITY

发明人:

Schneck Jonathan,Perica Karlo,Glick Bieler Joan,Oelke Mathias

申请号：

US201715790787

公开号：

US10098939(B2)

申请日:

2017.10.23

申请国别(地区):

美国

年份:

2018

代理人:

Morgan, Lewis & Bockius LLP

摘要：

Antigen-specific T cells, including nave T cells, and including rare precursor cells are enriched and expanded in culture. Enrichment and expansion provides a platform for more effective immunotherapy by adoptive transfer, as well as platforms for personalizing immunotherapy by determining T cell reactivity with a library of candidate peptide antigens.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/