Immunomodulating cyclic compounds from the BC loop of human PD1

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专利权人:

Aurigene Discovery Technologies Limited

发明人:

Sasikumar, Pottayil Govindan Nair,Ramachandra, Muralidhara

申请号：

AU2013239366

公开号：

AU2013239366A1

申请日:

2013.03.28

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

The present invention relates to novel cyclic compounds as therapeutic agents capable of inhibiting the programmed cell death 1 (PD1) signalling pathway. The invention also relates to derivative's of the therapeutic agents. The invention also encompasses the use of the said therapeutic agents and derivatives for treatment of disorders via immunopotentiation comprising inhibition of immunosuppressive signal induced due to PD-1, PD-L1, or PD-L2 and therapies using them.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/