GARY JOHN TRESADERN,MICHIEL LUC MARIA VAN GOOL,ANDRÉS AVELINO TRABANCO-SUÁREZ,SERGIO-ALVAR ALONSO-DE DIEGO,MARIA LUZ MARTIN-MARTIN,SUSANA CONDE-CEIDE,JOSÉ IGNACIO ANDRÉS-GIL,ÓSCAR DELGADO-GONZALEZ
申请号：
PT15744915
公开号：
PT3174883T
申请日:
2015.07.30
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 (“mGluR2”). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved.
