ШУЛЕР Элеанор Л. (US),НЭШ Дональд Э. (US),ПОУЛИНЕР Джеймс К. (US)
申请号:
RU2010146628/14
公开号:
RU2010146628A
申请日:
2009.04.17
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A method of treating a malignant neoplasm by inducing apoptosis, wherein the malignant neoplasm is one of the known types of malignant cells, comprising the steps of:! a. definition of a variety of malignant neoplasms, and! b. applying a disruptive electrical signal to a malignant neoplasm through contact or puncture of the cytoplasmic membrane of at least one malignant neoplasm cell; and using a disruptive electric signal to cause apoptosis. ! 2. The method according to claim 1, wherein the disturbing electrical signal is generated by! i. determining a resident electrical signal detected in a type of malignant neoplasm, and! ii. modifying a resident electrical signal to form a disturbing electrical signal. ! 3. The method according to claim 1, wherein the disturbing electrical signal is applied with a voltage of less than about 2 V.! 4. The method according to claim 1, wherein the disturbing electrical signal is applied with a current strength of less than about 70 μA. !5. The method according to claim 1, in which the stage of application is carried out using imulus. ! 6. The method according to claim 5, in which imulus contains many nanotubes. ! 7. The method according to claim 1, in which stage b includes the application of a disturbing electrical signal to a plurality of cancer cells located at a distance from each other. ! 8. A method of treating a malignant neoplasm by inducing apoptosis, comprising the steps of:! a. determination of a resident electrical signal detected in a malignant neoplasm1. Способ лечения злокачественного новообразования посредством вызывания апоптоза, где злокачественное новообразование представляет собой одну из известных разновидностей злокачественных клеток, включающий стадии: ! a. определение разновидности злокачественного новообразования, и ! b. применение нарушающего электрического сигнала к злокачественному новообразованию посредством контакта или прокола цитоплазматической мембраны, по меньшей мере, одной клетки злокачестве