KOPPITZ, Marcus M,.科皮茨,KLAR, Ulrich U,.克拉爾,JAUTELAT, Rolf R,.若泰拉特,KOSEMUND, Dirk D,.科澤蒙德,BOHLMANN, Rolf R,.博爾曼,BADER, Benjamin B,.巴德爾,LIENAU, Philip P,.利瑙,SIEMEISTER, Gerhard G,.西邁斯特
申请号：
HK14100804.0
公开号：
HK1187622B
申请日:
2014.01.24
申请国别(地区):
HK
年份:
2017
代理人:
摘要：
The present invention relates to substituted imidazopyrizine compounds of general formual (I): in which R1, R2, R3, R4 and R5 are as defined in the claims, to methods of and intermediates for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyper-proliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
