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TRICYCLIC FUSED PYRIDIN-2-ONE DERIVATIVES AND THEIR USE AS BRD4 INHIBITORS
专利权人:
JUBILANT BIOSYS LIMITED
发明人:
Saravanan VADIVELU,Sridharan RAJAGOPAL,Manjunatha M. RAMAIAH,Pavan Kumar GONDRALA,Murugan CHINNAPATTU,Dhanalakshmi SIVANANDHAN,Payal Kiran PARIKH,Chandrika MULAKALA
申请号:
US15754292
公开号:
US20180237453A1
申请日:
2016.09.08
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present disclosure describes heterocyclic compounds of Formula I or, its stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms and pharmaceutically active derivatives thereof and pharmaceutical compositions containing them as the active ingredient. The present disclosure also describes the synthesis and characterization of aforementioned compounds to exhibit high anticancer activity. The compounds of the present disclosure are useful as medicaments and their use in the manufacture of medicaments for treatment, prevention, or suppression of diseases, and conditions mediated by one or more BET family of bromodomains.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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