STAIDSON (BEIJING) BIOPHARMACEUTICALS CO., LTD.;BEIJING SOLOBIO GENETECHNOLOGY COMPANY LTD.
发明人:
WANG, Chao,ZHANG, Tingting,JIANG, Lixin
申请号:
SG11201909136P
公开号:
SG11201909136PA
申请日:
2018.03.26
申请国别(地区):
SG
年份:
2019
代理人:
摘要:
An shRNA expression cassette, a polynucleotide sequence carrying the same, and an use thereof. In an order of 5’ to 3’, the shRNA expression cassette sequentially includes a DNA sequence for expressing the shRNA and a stuffer sequence, and a sequence length of the shRNA expression cassette sequence is proximate to a length of a wild-type AAV genome. [Fig. 23]