Provided is artificial saliva including hyaluronic acid (HA) comprising 0.4 to 0.6 mg/ml of hyaluronic acid (HA), based on 100 parts by weight of the HA, 10 to 12 parts by weight of lysozyme, and 7 to 9 parts by weight of peroxidase. The artificial saliva may be used to treat xerostomia or oral candidiasis and can be effectively used to prevent or treat complications cased by reduced secretion of saliva, since the artificial saliva is in a physiological range of human saliva and shows adequate antimicrobial activities.本発明による人工唾液は、人体唾液内の生理的範囲内にあり、適した抗菌活性を示すので、口腔乾燥症または口腔カンジダ症の治療に使用されることができ、唾液分泌の低下による余病の予防または治療に有用に使用されることができる。
