Disclosed is a stable pharmaceutical formulation, comprising a fusion protein in which the extracellular ligand-binding domain of a human p75 tumor necrosis factor receptor is fused to the Fc domain of human IgG and a succinate buffering agent, without comprising a stabilizer. The stable pharmaceutical formulation enables the long-term storage of the TNFR-Fc fusion protein formulation and can exhibit superior storage stability without the need for demanding storage conditions, and is a simple formulation because no stabilizer is comprised therein and is thus more economical than other stabilizer-comprising formulations.在此揭示的是一種穩定藥學調配物，其包含一融合蛋白及一琥珀酸鹽緩衝劑，不含一穩定劑；其中在該融合蛋白內一人類p75腫瘤壞死因子受體之一細胞外配體結合結構域係被融合至一人類IgG之Fc結構域。該穩定藥學調配物使能夠長期貯存TNFR-Fc融合蛋白調配物，且能在不需要嚴格的貯存條件下展現優越的貯存穩定性，以及其為一簡單的調配物，因為其中不含穩定劑，因此比其它含穩定劑之調配物更經濟。
