Chang-Shan HSU,Wei-Hua HAO,Jong-Jing WANG,Tsung-Hsin LIN
申请号：
US16420581
公开号：
US20190275006A1
申请日:
2019.05.23
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides an oral self micro-emulsifying pharmaceutical composition of a hydrophilic drug or a pharmaceutically acceptable salt thereof which, in addition to the hydrophilic drug, one or more solvents for solving the hydrophilic drug to form a drug-solvent solution and a surfactant system, further comprises one or more hydrophilic carrier which are compatible with said drug-solvent solution and the surfactant system. The oral self micro-emulsifying pharmaceutical composition of the invention exhibits comparative bioavailability to that of the hydrophilic drug through injection and is stable during storage. A method for preparing the oral self micro-emulsifying pharmaceutical composition is also provided.
