BURNS, Aaron Craig,COLLINS, Michael Raymond,GREASLEY, Samantha Elizabeth,HOFFMAN, Robert Louis,HUANG, Qinhua,KANIA, Robert Steven,KUNG, Pei-Pei,LINTON, Maria Angelica,NARASIMHAN, Lakshmi Sourirajan,RI
申请号：
TN2016000459
公开号：
TN2016000459A1
申请日:
2015.04.17
申请国别(地区):
TN
年份:
2018
代理人:
摘要：
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R<；sup>；1<；/sup>；-R<；sup>；15<；/sup>； , w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
