SUMMARY A packing assembly for an axially movable spindle (1) extending from a casing (2) that is subjected to the pressure of an operating medium, said packing assembly comprising a plurality of stuffing-box annular packing elements (16, 18, 21, 23, 25, 27) disposed in-line in axially spaced relationship in an annular space (5) defined between the spindle (1) and the casing (2). The annular packing elements (16 ...) are axially biased from the interior (40) of the casing by a pressure transmitting element (6) which is under the agency of the operating medium.