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Compositions, suitable for oral administration, comprising a triazolo [4, 5-d]pyrimidin derivate
专利权人:
ASTRAZENECA AB
发明人:
BANKS, SIMON
申请号:
NZ57451407
公开号:
NZ574514A
申请日:
2007.08.20
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Discloses a pharmaceutical composition comprising: { 1 S-[1 0, 20, 313 (1 S*,2R*),513]} -3-(7 -{ [2-(3,4-difluorophenyl)cyclopropyl]amino} -5-(propylthio )-3H-1 ,2,3-triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol, a filler of the general structure (I) in the drawing which is a mixture of mannitol and dibasic calcium phosphate dehydrate, a binder which is hydroxypropyl cellulose, disintegrant which is sodium starch glycollate and one or more lubricants. The pharmaceutical composition disclosed has a therapeutic application in the treatment of thrombosis associated conditions.
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