ASTRAZENECA UK LIMITED;BRISTOL-MYERS SQUIBB COMPANY
发明人:
ABEBE, ADMASSU,MARTIN, KYLE,PATEL, JATIN M.,DESAI, DIVYAKANT,TIMMINS, PETER
申请号:
CA2780939
公开号:
CA2780939C
申请日:
2010.11.12
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to bilayer tablet formulations comprising metformin extended release (XR) or reduced mass metformin XR formulation as the first layer, an SGLT2 inhibitor formulation as the second layer, and optionally a film coating. The present invention provides methods of preparing the bilayer tablet formulations and methods of treating diseases or disorders associated with SGLT2 activity employing the bilayer tablet formulations.