Methods and compositions for oral administration of protein and peptide therapeutic agents

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专利权人:

Orna Gribova;Alexander Vol

发明人:

Alexander Vol,Orna Gribova

申请号：

US12811871

公开号：

US08936786B2

申请日:

2009.01.08

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention provides a pharmaceutical composition formulated for oral delivery, comprising a particulate non-covalently associated mixture of pharmacologically inert silica nanoparticles having a hydrophobic surface, a polysaccharide, and a biologically active protein or peptide suspended in an oil. The present invention further provides methods of manufacturing same and therapeutic methods utilizing same for oral delivery of a therapeutic protein or peptide.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/