BioNTech RNA Pharmaceuticals GmbH;TRON - Translationale Onkologie an der Universitaetsmedizin der Johannes Gutenberg - Universitaet Mainz gemeinnuetzige GmbH
发明人:
SAHIN Ugur,HAAS Heinrich,KREITER Sebastian,DIKEN Mustafa,FRITZ Daniel,MENG Martin,KRANZ Lena Mareen,REUTER Kerstin
申请号：
SI201331402
公开号：
SI2830593T1
申请日:
2013.03.25
申请国别(地区):
SI
年份:
2019
代理人:
摘要：
The present invention is in the field of immunotherapy, in particular tumor immunotherapy. The present invention provides pharmaceutical formulations for delivering RNA to antigen presenting cells such as dendrite cells (DCs) in the spleen after systemic administration. In particular, the formulations described herein enable to induce an immune response after systemic administration of antigen-coding RNA.
