The present invention provides an analysis and method of quantifying the severity of skin diseases through the skin exhibited entropy. Quantitative analysis and evaluation of skin is a new, non-invasive, quick, and reproducible method of assessing skin disease and skin disease progression. The quantitative analysis of the skin disease applies a entropy algorithm to quantify the severity of the disease and compared to healthy skin. The method is applied in determination of the severity of the skin disease or applied to determine the effectiveness of the subsequent treatment modalities. It is highly reproducible and removes physician's own bias and past experience.
