CIBLAGE DE PHOSPHODIESTERASES ASSOCIEES AU CGMP AFIN DE REDUIRE LA FORMATION DE KYSTES DANS LES MALADIES KYSTIQUES RENALES, AINSI QUE PROCEDES ASSOCIES ET MATIERES ASSOCIEES
CUNHA DE ALMEIDA, RITA MARIA;INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION
发明人:
CUNHA DE ALMEIDA, RITA MARIA,BACALLAO, ROBERT,CLENDENON, SHERRY G.,GLAZIER, JAMES A.
申请号:
CA2982436
公开号:
CA2982436A1
申请日:
2016.03.14
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
Described herein is the identification of cGMP-specific phosphodiesterase upregulation in cystic kidney diseases. Also described is the use of cGMP-specific phosphodiesterase inhibitors for preventing the progression and/or treatment of cystic kidney diseases. Other aspects described provide medicaments for preventing the progression and/or treating cystic kidney diseases, and methods of diagnosing cystic kidney disease.