Mark E. Arnoldussen,Jonathan Wong,Benjamin A. Logan,Leander Zickler
申请号：
US12121635
公开号：
US08926600B2
申请日:
2008.05.15
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Systems and methods for removing an epithelial layer disposed over a stromal layer in a cornea irradiate a region of the epithelial layer with a pulsed beam of ablative radiation. The ablative radiation is scanned to vary the location of the beam within the region in accordance with a pulse sequence. The pulse sequence is arranged to enhance optical feedback based on a tissue fluorescence of the epithelial layer. The penetration of the epithelial layer is detected in response to the optical feedback. The use of scanning with the pulse sequence arranged to enhance optical feedback allows large areas of the epithelium to be ablated such penetration of the epithelial layer can be detected.
