CONSTRUCTION D'UN RÉCEPTEUR D'ANTIGÈNE CHIMÈRE CIBLANT UN ANTIGÈNE CD20 ET IDENTIFICATION D'ACTIVITÉ DE LYMPHOCYTES T GÉNÉTIQUEMENT MODIFIÉES DE CELUI-CI
Cellular Biomedicine Group (Wuxi) Ltd.;Cellular Biomedicine Group (Shanghai) Ltd.
发明人:
申请号：
EP18751050.8
公开号：
EP3599251A1
申请日:
2018.02.08
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
Provided are a chimeric antigen receptor targeting CD20 antigen and a preparation method thereof. The extracellular antigen binding domain of the chimeric antigen receptor includes an antibody heavy chain variable region shown in SEQ ID NO: 7 or 9 or 33 and an antibody light chain variable region shown in SEQ ID NO: 11 or 13 or 35, and is capable of killing tumor cells.
