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Platelet-Derived Growth Factor Formulations for Enhancing Spine Fusion
专利权人:
LLC;BioMimetic Therapeutics
发明人:
Sharath Sundararaj,Robert K. Shockley,Conan S. Young,Carrie Browning
申请号:
US16820219
公开号:
US20200297897A1
申请日:
2020.03.16
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure provides improved compositions comprising a solution of a platelet-derived growth factor and a biocompatible matrix that are useful for bone fusion procedures, such as spine fusion procedures. The compositions advantageously comprise a the PDGF solution and biocompatible matrix in about a 2:1 volume to weight (mL:g) ratio such that the compositions can be readily applied to a site of bone fusion using a syringe or cannula. In particular embodiments, the composition is useful in conjunction with a spine fusion cage in a spine fusion procedure. The present disclosure also provides methods of performing fusion procedures, such as spine fusion, and kits for fusion procedures.
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