BAE IN HWAN,SON JUNG BEOM,HAN SANG MI,KWAK EUN JOO,SONG JI YOUNG,BYUN EUN YOUNG,JUN SEUNG AH,AHN YOUNG GIL,SUH KWEE HYUN,KIM HO SEOK
申请号：
NZ62801312
公开号：
NZ628013A
申请日:
2012.12.27
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed are thienopyrimidine derivative compounds of formula (I), wherein the substituents are as defined in the specification. The compounds have inhibitory activity for protein kinase, useful for the prevention and treatment of abnormal cell growth diseases such as cancer. Examples of a compound of formula (I) are: 4-amino-N-(1-((4-chlorophenyl)amino)-6-methylisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide 4-(cyclopropylamino)-N-(6-methyl-1-((3-(trifluoromethyl)phenyl)amino)isoquinolin-5-yl)thieno [3,2-d]pyrimidine-7-carboxamide
