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TOLL-LIKE RECEPTOR 7 (TLR7) AGONISTS HAVING A HETEROBIARYL MOIETY, CONJUGATES THEREOF, AND METHODS AND USES THEREFOR
专利权人:
BRISTOL-MYERS SQUIBB COMPANY
发明人:
Liqi HE,Sanjeev GANGWAR,Shoshana L. POSY,Yam B. POUDEL,Prasanna SIVAPRAKASAM
申请号:
US16659735
公开号:
US20200048254A1
申请日:
2019.10.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Compounds having a structure according to formula (I) or (II)where R1, R2, and Ar are as defined herein, are agonists for the Toll-like receptor 7 (TLR7) and can be used as adjuvants for stimulating the immune system. Some such compounds can be used in conjugates for targeted delivery to the organ or tissue of intended action.
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中国工程科技知识中心
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http://www.ckcest.cn/home/
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