The invention is a hand-held advanced ovulation predictor device, which includes an advanced ovulation predictor device body, an optical subassembly containing one or more hybrid lenses, an electronics assembly with a light source, switch, and battery, and, optionally, a cover. The preferred embodiment of this invention is one in which the viewing axis and the device axis are not collinear or coaxial, the specimen is illuminated with oblique or dark field illumination, the method of transmitting the light is through a light pipe, and one or more lenses are hybrid lenses.
