PROBLEM TO BE SOLVED: To provide pharmaceuticals, food products, cosmetics or the like which have Nrf2 expression promoting effects and exhibiting the effects of increasing antioxidant protection and detoxication ability of a living body, or materials blended therein.SOLUTION: The Nrf2 activator comprises methoxychalcone represented by the general formula (1), where R represents a hydrogen atom or a methyl group, as an active ingredient.
