Use of at Least One Isoquinoline Compound of Formula I, Pharmaceutical Composition for Treating or Preventing Neurodegenerative Diseases and Method for Treating or Preventing Neurodegenerative Diseases
Luiz Francisco Pianowski,Joäo Batista Calixto,Jan A. Glinski
申请号:
US13574215
公开号:
US20120302593A1
申请日:
2011.01.19
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention concern the use of isoquinoline alkaloid compounds of formula I in the preparation of pharmaceutical compositions useful in the treatment of neurodegenerative diseases, particularly Alzheimers disease, as well as pharmaceutical composition comprising said compounds and method of treatment of neurodegenerative diseaseswherein R1 is —OH or —OCH3, and X is non-existent, HCl or HBr, including their isomers,