Massachusetts Institute of Technology;National University of Singapore
发明人:
Zhiyong Poon,Wong Cheng Lee,Krystyn J. Van Vliet
申请号：
US15119534
公开号：
US10047344B2
申请日:
2015.02.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention provides, inter alia, populations of large mesenchymal stem cells (MSC)(as well as conditioned medium from these cells) with enhanced regenerative potential, as well as methods of culturing and using these populations, such as therapeutic methods of mediating tissue repair or enhancing homing and engraftment of hematopoietic stem cells. These large MSC populations can, in certain embodiments, be produced by biophysically sorting an MSC-containing population.
