GIBSON Robert (AU),ГИБСОН Роберт (AU),GE Liu (AU),ГЭ Лю (AU)
申请号:
RU2014132765
公开号:
RU0002639455C2
申请日:
2013.01.11
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
FIELD: chemistry.SUBSTANCE: invention relates to a method of stabilizing fatty acids present in the sample, such as biological fluids (e.g., blood, saliva, breast milk, urine, semen, plasma and blood serum), wherein the method involves applying fatty acids or the sample containing fatty acids to the solid medium that contains a firm substrate, at least, one chelate-forming tool, and, at least, one antioxidant, where a solid substrate contains less than 2 μg/cm2 of impurities where impurities constitute one or more compounds selected from the group consisting of saturated fatty acids, esters of saturated fatty acids, resin acids and esters of resin acids. The present invention further relates to the method of determining the composition of fatty acids in the sample when stored on such medium. Wherein the method involves: (a) applying the sample to the solid medium containing a solid substrate, at least, one chelate-forming tool, and, at least, one antioxidant, where the solid substrate contains less than 2 μg/cm2 of impurities, whereby the sample becomes sorbed on the solid substrate; (b) determining the composition of fatty acids in the sample, sorbed on the solid substrate, where impurities are one or more compounds selected from the group consisting of saturated fatty acids, esters of saturated fatty acids, resin acids and esters of resin acids. The invention also relates to a solid medium and a method for its production.EFFECT: increasing the efficiency.74 cl, 8 dwg, 13 tblНастоящее изобретение относится к способу стабилизации жирных кислот, присутствующих в образце, таком как биологические жидкости (например, кровь, слюна, грудное молоко, моча, сперма, плазма и сыворотка крови), причем способ предусматривает нанесение жирных кислот или образца, содержащего жирные кислоты, на твердый носитель, который содержит твердую подложку, по меньшей мере одно хелатообразующее средство и по меньшей мере один антиоксидант, где твердая подложка содержит менее 2 мкг/см2 примесе