Human anti-α9 integrin antibody

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专利权人:

一般財団法人化学及血清療法研究所

发明人:

鳥飼 正治,石川 大輔,中島 敏博,樋口 浩文,酒井 文彦,山本 宣哉,藤田 大雅,田口 克成

申请号：

JP2009548111

公开号：

JP5371779B2

申请日:

2008.12.26

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The present invention provides a human anti-±9 integrin antibody or an antibody fragment which specifically recognize human ±9 integrin and mouse ±9 integrin, inhibit interaction with their ligands, particularly, the antibody or antibody fragment which recognize loop regions of human and mouse ±9 integrins, a gene encoring the antibody or antibody fragment, a recombinant expression vector containing the gene, a transformant harboring the gene, production method of human anti-±9 integrin antibody or antibody fragment using the transformant, and an agent for the prophylaxis or treatment of rheumatoid arthritis which contains the antibody or antibody fragment.

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