The present invention relates to a screening method to identify mucus- penetrating compounds. In certain aspects, the present invention relates to mucus- penetrating peptides and constructs comprising an agent, such as a therapeutic agent, imaging agent or diagnostic agent, conjugated to a mucus-penetrating peptide.Linvention concerne un procédé de criblage permettant didentifier des composés pénétrant le mucus. Dans certains aspects, linvention concerne des peptides pénétrant le mucus et des constructions comprenant un agent, tel quun agent thérapeutique, un agent dimagerie ou un agent de diagnostic, conjugués à un peptide pénétrant le mucus.
