Bin Liu,Jinjun Shao,Youyong Yuan,Jing Liang,Benzhong Tang,Zhegang Song,Yilong Chen,Tsz Kin Kwok
申请号:
US15114692
公开号:
US20160356723A1
申请日:
2015.01.27
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention is drawn toward luminogens and chemical compositions comprising a target recognition motif, a hydrophilic moiety, a linking moiety, and at least one luminogen. Additionally presented are methods of: assessing the conversion of a prodrug into its active form, assessing the therapeutic efficacy of a prodrug, detecting glutathione in a biological sample, detecting alkaline phosphatase in a sample, and conducting fluorescence imaging or magnetic resonance imaging with the use of luminogen-containing compositions.