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4-morpholino-thienopyrimidine derivatives, process for their preparation and pharmaceutical compositions comprising them for treating diseases or disorders
专利权人:
F. HOFFMANN-LA ROCHE AG
发明人:
申请号:
IL19476208
公开号:
IL194762A
申请日:
2008.10.22
申请国别(地区):
IL
年份:
2014
代理人:
摘要:
Compounds of Formulae la and Ib, and stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formula la and Ib for in vitro , in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
来源网站:
中国工程科技知识中心
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