(1-AZA-BICYCLO[3.3.1]NON-4-YL)-[5-(1H-INDOL-5-YL)-HETEROARYL]-AMINES EN TANT QUE LIGANDS CHOLINERGIQUES DU N-ACHR DANS LE TRAITEMENT DE TROUBLES PSYCHOTIQUES ET NEURODEGENERATIFS
FREDERIKSEN, MATHIAS,FEUERBACH, DOMINIK,HURTH, KONSTANZE,KOLLER, MANUEL,ROY, BERNARD LUCIEN
申请号：
CA2632893
公开号：
CA2632893C
申请日:
2006.12.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to compounds of formula (I) wherein n represents0, 1, 2, 3, 4 or 5, R represents independent from each other hydroxyl, cyano,nitro, halogen, alkyl, alkoxy alkylcarbonyl, alkoxycarbonyl, alkylamine,dialkylamine, alkylcarbonylamine, alkylcarbamate Y represents one of thefollowing groups: (Ia) in free base or acid addition salt form, to processesfor their production, to pharmaceutical compositions comprising them and theiruse in the manufacture of a medicament for the treatment and/or delay ofprogression of psychotic and neurodegenerative disorders.
