Sumith A. Kularatne,Pravin Gagare,Ananda Kumar Kanduluru
申请号：
US16723319
公开号：
US20200174009A1
申请日:
2019.12.20
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to compounds that are useful as near-infrared fluorescence probes, wherein the compounds include i) a ligand that binds to the active site of carbonic anhydrase, ii) a dye molecule, and iii) a linker molecule that comprises an amino acid, amide, ureido, or polyethylene glycol derivative thereof. The disclosure further describes methods and compositions for making and using the compounds, methods incorporating the compounds, and kits incorporating the compounds.
