KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY;HANDOK INC.
发明人:
Hee Jung Jung,Jae Du Ha,Sung Yun Cho,Hyoung Rae Kim,Kwang Ho Lee,Chong Ock Lee,Sang Un Choi,Chi Hoon Park
申请号:
US14435974
公开号:
US09403831B2
申请日:
2013.09.30
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to a novel triazolopyrazine derivative or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same as an active ingredient for preventing or treating hyper proliferative disorder. The present invention can be useful as a therapeutic agent for various hyper proliferative disorders associated with excessive cell proliferation and growth caused by abnormal kinase activity, such as cancer, psoriasis, rheumatoid arthritis, and diabetic retinopathy, by efficiently inhibiting c-Met tyrosine kinase activity.