Inhibitors of bromodomains as modulators of gene expression

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专利权人:

Icahn School of Medicine at Mount Sinai

发明人:

Zhou, Ming-Ming,Ohlmeyer, Michael,Mujtaba, Shiraz,Plotnikov, Alexander,Kastrinsky, David,Zhang, Guangtao

申请号：

AU2012220620

公开号：

AU2012220620A1

申请日:

2012.02.23

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

This disclosure relates generally to compounds and compositions comprising one or more diphenylethylene, diphenylethylyne, and azobenzene analogs. These compounds are useful for treating diseases associated with NF-kB and p53 activity, such as cancer and inflammatory disease.

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