THIS INVENTION PROVIDES DIFFERENT USES OF RECOMBINANT SUPER- COMPOUND INTERFERONS(RSIFN-COS) AND ITS EGUIVALENT WITH CHANGED SPATIAL CONFIGURATION,HIGH EFFICACY AND LOW SIDE EFFECTS.THEREFORE,HIGH DOSE OF RNSIFN-CO MAY BE USED.ONE CHARACTERISTI OF RSIFN-CO IS ITS ABILITY TO INHIBIT THE HBV DNA DUPLICATION AND SECRETION OF HBSAG AND HBEAG IN VITRO PHARMACOLOGICAL STUDIES.THE CYTOTOXIC EFFECT OF RSIFN-CO IS ONLY ONE-EIGHTH (1/8) OF CURRENTLY CLINICALLY AVAILABLE INTERFERONS BUT ITS ANTI-VIRAL EFFECT IS APPROXIMATELY FIVE TO TWENTY (5-20) TIMES HIGHER,AND WHEN USED IN VIVO IT HAS A BROADER SPECTRUM OF CLINICAL APPLICATIONS AND LONGER BOIFEEDBACK RESPONDSE.THIS INVENTION FURTHER PROVIDES SUPER-COMPOUND INTERFERON OR ITS EQUIVALENT,SYNTHESIS OF ARTIFICIAL GENE WITH CODON PREFERENCE WHICH CODES FOR SAID RSIFN-CO AND ITS EQUIVALENT,VECTOR COMPRISING SAID GENE AND APPROPRIATE EXPRESSION SYSTEM FOR EXPRESSION OF SAID RSIFN-CO.FINALLY THIS INVENTION PROVIDES THE SUPER-COMPOUND INTERFERON (RSIFN-CO) AND ITS EQUIVALENT,A PROCESS TO PRODUCE SAME USES THEREOF.
