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heterociklilsulfonil aminometil hetero arilno substituirani H pirolni derivati kot inhibitorji izločanja kisline
专利权人:
TEKEDA PHARMACEUTICAL COMPANY LIMITED
发明人:
KAJINO MASAHIRO,HASUOKA ATSUSHI,NISHIDA HARUYUKI
申请号:
SI200631443
公开号:
SI2327692T1
申请日:
2006.08.29
申请国别(地区):
SI
年份:
2012
代理人:
摘要:
A compound represented by the formula (I): wherein R 1 is a monocyclic nitrogen-containing heterocyclic group optionally condensed with a benzene ring or a heterocycle, the monocyclic nitrogen-containing heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R 2 is an optionally substituted C 6-14 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R 3 and R 4 are each a hydrogen atom, or one of R 3 and R 4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R 5 is an alkyl group, or a salt thereof, for use for the treatment or prophylaxis of peptic ulcer, Zollinger-Ellison syndrome, gastritis, erosive esophagitis, reflux esophagitis, symptomatic gastroesophageal reflux disease (Symptomatic GERD), functional dyspepsia, gastric cancer, stomach MALT lymphoma, or gastric hyperacidity; or the inhibition of upper gastrointestinal hemorrhage due to peptic ulcer, acute stress ulcer, hemorrhagic gastritis or invasive stress, or for use for the eradication of helicobacter pylori.
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