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The purposes of the upper gland Ji Su Tone Festival Elixirs of Kidney
专利权人:
Novartis AG;诺华股份有限公司;諾華股份有限公司
发明人:
胡琦颖,胡琦穎,G.克桑德,E.梅瑞迪斯,L.G.莫诺维茨,L.G.莫諾維茨,J.帕皮咏,J.帕皮詠,C.舒马赫,C.舒馬赫,G.克桑德,E.梅瑞迪斯,L.G.莫诺维茨,L.G.莫諾維茨,J.帕皮咏,J.帕皮詠,C.舒马赫,C.舒馬赫
申请号:
MOJ001919
公开号:
MOJ001919B
申请日:
2015.10.23
申请国别(地区):
MO
年份:
2016
代理人:
摘要:
This Hair is bright to be related to controlling Treatment Right as the method for disease Huo Shi Tone with what,The disease He Shi Tone swashs hormonal readiness and/or reduced androgen levels as characteristic using the Should that improves,The method Bao Kuo Give gives the Right and receives Which as controlling Ke on a effective amount of formula of Treatment (I) compound or Qi Drug Learn: wherein n is 1 or 3; R is Hydrogen or-C (O) N (Ra) (Rb),Wherein Ra and Rb Independence is on the spot-(C1-C4) alkyl or-(C1-C4) alkyl-(C5-C7) aryl,Wherein Ra and Rb respectively Ren Election quilt-(C1-C4) alkoxy replace; R1,R2 and R3 Independence be on the spot Hydrogen,Halogen element,Cyano or-(C6-C10) aryl,Wherein described-(C6-C10) aryl is replaced with appointing Election by Halogen element,Strip part be R1,Most Ge are Hydrogen in R2 and R3; And R4 and R5 are Hydrogen.本發明涉及用於治療對象疾病或失調的方法,所述疾病和失調以提高的應激激素水平和/或降低的雄激素水平爲特徵,所述方法包括給予所述對象治療有效量的式(I)化合物或其藥學上可接受的鹽:其中n是1或3;R是氫或-C(O)N(Ra)(Rb),其中Ra和Rb獨立地是-(C1-C4)烷基或-(C1-C4)烷基-(C5-C7)芳基,其中Ra和Rb各自任選地被-(C1-C4)烷氧基取代;R1、R2和R3獨立地是氫、鹵素、氰基或-(C6-C10)芳基,其中所述-(C6-C10)芳基任選地被鹵素取代,條件是R1、R2和R3中最多一個是氫;以及R4和R5是氫。
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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