Jeremiah F. ROETH,Charles C. REED,Brandon CUTHERTSON,Sunil CHADA,William E. FOGLER,Fayaz KHAZI
申请号：
US15993773
公开号：
US20180344876A1
申请日:
2018.05.31
申请国别(地区):
US
年份:
2018
代理人:
摘要：
This invention relates to the field of therapeutics. Disclosed are methods of generating conditionally expressing erythropoietin under the control of an ecdysone receptor-based gene expression modulation system in the presence of activating ligand and uses for therapeutic purposes in animals. The methods of the invention cause an in vivo increase in the expression of erythropoietin and an increase in the hematocrit or volume percentage of red blood cells in blood after administration of the ligand.
