METHOD FOR SIMULTANEOUSLY DETECTING FLUORESCENCE AND RAMAN SIGNALS FOR MULTIPLE FLUORESCENCE AND RAMAN SIGNAL TARGETS, AND MEDICAL IMAGING DEVICE FOR SIMULTANEOUSLY DETECTING MULTIPLE TARGETS USING THE METHOD
Dae Hong JEONG,Keon Wook KANG,Dong Soo LEE,Yoon Sik LEE,Gun Sung KIM,Bong Hyun JUN,Jin Chul PAENG,Ho Young LEE,Yun Sang LEE
申请号:
US15398038
公开号:
US20170112380A1
申请日:
2017.01.04
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Provided are a method for simultaneously detecting fluorescence and Raman signals for multiple fluorescence and Raman signal targets, and a medical imaging device for simultaneously detecting multiple targets using the method. The method includes: injecting at least one marker particle comprising Raman markers and receptors into the body of an animal, which can be a human irradiating a laser beam onto the body of the animal and detecting the optical signals emitted by the marker particle after the irradiation of the laser beam separately as fluorescence signals and Raman signals. The simultaneous detection of multiple targets may be performed even without scanning optical signals emitted by the marker particle individually with different optical fibers. As an examination may be performed by injecting surface-enhanced Raman marker particles, weak Raman signals may be augmented so as to obtain a more accurate diagnosis result in real time.